8.5. Extracting root sum of squares from edge-wise timeseries.#

This example uses a RSSETSMarker to compute root sum of squares of the edge-wise timeseries using the Schaefer parcellation (100 rois and 200 rois, 17 Yeo networks) for a 4D nifti BOLD file.

Authors: Leonard Sasse, Sami Hamdan, Nicolas Nieto, Synchon Mandal

License: BSD 3 clause

import tempfile

import junifer.testing.registry  # noqa: F401
from junifer.api import collect, run
from junifer.storage import SQLiteFeatureStorage
from junifer.utils import configure_logging

Set the logging level to info to see extra information:

configure_logging(level="INFO")
2024-04-30 13:12:43,238 - JUNIFER - INFO - ===== Lib Versions =====
2024-04-30 13:12:43,238 - JUNIFER - INFO - numpy: 1.26.4
2024-04-30 13:12:43,238 - JUNIFER - INFO - scipy: 1.11.4
2024-04-30 13:12:43,238 - JUNIFER - INFO - pandas: 2.1.4
2024-04-30 13:12:43,238 - JUNIFER - INFO - nilearn: 0.10.2
2024-04-30 13:12:43,238 - JUNIFER - INFO - nibabel: 5.2.1
2024-04-30 13:12:43,238 - JUNIFER - INFO - junifer: 0.0.5.dev48
2024-04-30 13:12:43,238 - JUNIFER - INFO - ========================

Define the DataGrabber interface

datagrabber = {
    "kind": "SPMAuditoryTestingDataGrabber",
}

Define the markers interface

markers = [
    {
        "name": "Schaefer100x17_RSSETS",
        "kind": "RSSETSMarker",
        "parcellation": "Schaefer100x17",
    },
    {
        "name": "Schaefer200x17_RSSETS",
        "kind": "RSSETSMarker",
        "parcellation": "Schaefer200x17",
    },
]

Create a temporary directory for junifer feature extraction: At the end you can read the extracted data into a pandas.DataFrame.

with tempfile.TemporaryDirectory() as tmpdir:
    # Define the storage interface
    storage = {
        "kind": "SQLiteFeatureStorage",
        "uri": f"{tmpdir}/test.sqlite",
    }
    # Run the defined junifer feature extraction pipeline
    run(
        workdir=tmpdir,
        datagrabber=datagrabber,
        markers=markers,
        storage=storage,
        elements=["sub001"],  # we calculate for one subject only
    )
    # Collect extracted features data
    collect(storage=storage)
    # Create storage object to read in extracted features
    db = SQLiteFeatureStorage(uri=storage["uri"])

    # List all the features
    print(db.list_features())
    # Read extracted features
    df_vbm = db.read_df(feature_name="BOLD_Schaefer100x17_RSSETS")
2024-04-30 13:12:43,239 - JUNIFER - INFO - Validating Marker Collection
2024-04-30 13:12:43,239 - JUNIFER - INFO - DataGrabber output type: ['BOLD', 'T1w']
2024-04-30 13:12:43,239 - JUNIFER - INFO - Validating Data Reader:
2024-04-30 13:12:43,239 - JUNIFER - INFO - Data Reader output type: ['BOLD', 'T1w']
2024-04-30 13:12:43,239 - JUNIFER - INFO - Validating Marker: Schaefer100x17_RSSETS
2024-04-30 13:12:43,239 - JUNIFER - INFO - Marker output type: ['timeseries']
2024-04-30 13:12:43,239 - JUNIFER - INFO - Validating storage for Schaefer100x17_RSSETS
2024-04-30 13:12:43,239 - JUNIFER - INFO - Validating Marker: Schaefer200x17_RSSETS
2024-04-30 13:12:43,239 - JUNIFER - INFO - Marker output type: ['timeseries']
2024-04-30 13:12:43,239 - JUNIFER - INFO - Validating storage for Schaefer200x17_RSSETS
2024-04-30 13:12:43,239 - JUNIFER - INFO - Getting element sub001
2024-04-30 13:12:45,690 - JUNIFER - INFO - Fitting pipeline
2024-04-30 13:12:45,690 - JUNIFER - INFO - Reading BOLD from /tmp/tmpdy0loykc/sub001_bold.nii.gz
2024-04-30 13:12:45,690 - JUNIFER - INFO - BOLD is type NIFTI
2024-04-30 13:12:45,691 - JUNIFER - INFO - Reading T1w from /tmp/tmpdy0loykc/sub001_T1w.nii.gz
2024-04-30 13:12:45,691 - JUNIFER - INFO - T1w is type NIFTI
2024-04-30 13:12:45,692 - JUNIFER - INFO - Fitting marker Schaefer100x17_RSSETS
2024-04-30 13:12:45,692 - JUNIFER - INFO - Computing BOLD
2024-04-30 13:12:45,692 - JUNIFER - INFO - Fetching one of Schaefer parcellations.
2024-04-30 13:12:45,692 - JUNIFER - INFO - Parcellation parameters:
2024-04-30 13:12:45,692 - JUNIFER - INFO -      resolution: 3.0
2024-04-30 13:12:45,692 - JUNIFER - INFO -      n_rois: 100
2024-04-30 13:12:45,692 - JUNIFER - INFO -      yeo_networks: 17
2024-04-30 13:12:45,692 - JUNIFER - INFO - At least one of the parcellation files are missing. Fetching using nilearn.
Downloading data from https://raw.githubusercontent.com/ThomasYeoLab/CBIG/v0.14.3-Update_Yeo2011_Schaefer2018_labelname/stable_projects/brain_parcellation/Schaefer2018_LocalGlobal/Parcellations/MNI/Schaefer2018_100Parcels_17Networks_order.txt ...
 ...done. (0 seconds, 0 min)
Downloading data from https://raw.githubusercontent.com/ThomasYeoLab/CBIG/v0.14.3-Update_Yeo2011_Schaefer2018_labelname/stable_projects/brain_parcellation/Schaefer2018_LocalGlobal/Parcellations/MNI/Schaefer2018_100Parcels_17Networks_order_FSLMNI152_2mm.nii.gz ...
 ...done. (0 seconds, 0 min)
2024-04-30 13:12:45,924 - JUNIFER - INFO - Loading parcellation /home/runner/junifer/data/parcellations/schaefer_2018/Schaefer2018_100Parcels_17Networks_order_FSLMNI152_2mm.nii.gz
2024-04-30 13:12:45,954 - JUNIFER - INFO - Found existing xfm file for MNI152NLin6Asym to MNI152Lin at /home/runner/junifer/data/xfms/MNI152NLin6Asym_to_MNI152Lin/MNI152NLin6Asym_to_MNI152Lin_Composite.h5
2024-04-30 13:12:46,990 - JUNIFER - INFO - Downloading template MNI152Lin in resolution 2
2024-04-30 13:12:47,087 - JUNIFER - INFO - antsApplyTransforms command to be executed:
antsApplyTransforms -d 3 -e 3 -n 'GenericLabel[NearestNeighbor]' -i /tmp/tmp1q1papv3/parcellationse04yfval/Schaefer100x17.nii.gz -r /tmp/tmp1q1papv3/parcellationse04yfval/MNI152Lin_T1w_3.0.nii.gz -t /home/runner/junifer/data/xfms/MNI152NLin6Asym_to_MNI152Lin/MNI152NLin6Asym_to_MNI152Lin_Composite.h5 -o /tmp/tmpt4t2mbgo/parcellationsjfjdva4y/Schaefer100x17_warped_from_MNI152NLin6Asym_to_MNI152Lin.nii.gz
2024-04-30 13:12:48,482 - JUNIFER - INFO - antsApplyTransforms command succeeded with the following output:
b''
2024-04-30 13:12:51,147 - JUNIFER - INFO - Storing in <SQLiteFeatureStorage @ /tmp/tmp66v30c4q/test.sqlite (multiple output)>
2024-04-30 13:12:51,166 - JUNIFER - INFO - Fitting marker Schaefer200x17_RSSETS
2024-04-30 13:12:51,166 - JUNIFER - INFO - Computing BOLD
2024-04-30 13:12:51,167 - JUNIFER - INFO - Fetching one of Schaefer parcellations.
2024-04-30 13:12:51,167 - JUNIFER - INFO - Parcellation parameters:
2024-04-30 13:12:51,167 - JUNIFER - INFO -      resolution: 3.0
2024-04-30 13:12:51,167 - JUNIFER - INFO -      n_rois: 200
2024-04-30 13:12:51,167 - JUNIFER - INFO -      yeo_networks: 17
2024-04-30 13:12:51,167 - JUNIFER - INFO - At least one of the parcellation files are missing. Fetching using nilearn.
Downloading data from https://raw.githubusercontent.com/ThomasYeoLab/CBIG/v0.14.3-Update_Yeo2011_Schaefer2018_labelname/stable_projects/brain_parcellation/Schaefer2018_LocalGlobal/Parcellations/MNI/Schaefer2018_200Parcels_17Networks_order.txt ...
 ...done. (0 seconds, 0 min)
Downloading data from https://raw.githubusercontent.com/ThomasYeoLab/CBIG/v0.14.3-Update_Yeo2011_Schaefer2018_labelname/stable_projects/brain_parcellation/Schaefer2018_LocalGlobal/Parcellations/MNI/Schaefer2018_200Parcels_17Networks_order_FSLMNI152_2mm.nii.gz ...
 ...done. (0 seconds, 0 min)
2024-04-30 13:12:51,382 - JUNIFER - INFO - Loading parcellation /home/runner/junifer/data/parcellations/schaefer_2018/Schaefer2018_200Parcels_17Networks_order_FSLMNI152_2mm.nii.gz
2024-04-30 13:12:51,414 - JUNIFER - INFO - Found existing xfm file for MNI152NLin6Asym to MNI152Lin at /home/runner/junifer/data/xfms/MNI152NLin6Asym_to_MNI152Lin/MNI152NLin6Asym_to_MNI152Lin_Composite.h5
2024-04-30 13:12:52,476 - JUNIFER - INFO - Downloading template MNI152Lin in resolution 2
2024-04-30 13:12:52,573 - JUNIFER - INFO - antsApplyTransforms command to be executed:
antsApplyTransforms -d 3 -e 3 -n 'GenericLabel[NearestNeighbor]' -i /tmp/tmp1q1papv3/parcellations5nv0_03b/Schaefer200x17.nii.gz -r /tmp/tmp1q1papv3/parcellations5nv0_03b/MNI152Lin_T1w_3.0.nii.gz -t /home/runner/junifer/data/xfms/MNI152NLin6Asym_to_MNI152Lin/MNI152NLin6Asym_to_MNI152Lin_Composite.h5 -o /tmp/tmpt4t2mbgo/parcellationsw7x4g_vw/Schaefer200x17_warped_from_MNI152NLin6Asym_to_MNI152Lin.nii.gz
2024-04-30 13:12:54,596 - JUNIFER - INFO - antsApplyTransforms command succeeded with the following output:
b''
2024-04-30 13:12:56,648 - JUNIFER - INFO - Storing in <SQLiteFeatureStorage @ /tmp/tmp66v30c4q/test.sqlite (multiple output)>
2024-04-30 13:12:56,669 - JUNIFER - INFO - Marker collection fitting done
2024-04-30 13:12:56,670 - JUNIFER - INFO - Collecting data using SQLiteFeatureStorage
2024-04-30 13:12:56,671 - JUNIFER - INFO - Collecting data from /tmp/tmp66v30c4q/*test.sqlite

file: 0it [00:00, ?it/s]

feature:   0%|          | 0/2 [00:00<?, ?it/s]
feature: 100%|██████████| 2/2 [00:00<00:00, 60.87it/s]

file: 1it [00:00, 22.27it/s]
2024-04-30 13:12:56,716 - JUNIFER - INFO - Collect done
{'1d81ad1f44011f6c4d7e180b2e69045a': {'datagrabber': {'class': 'SPMAuditoryTestingDataGrabber', 'types': ['BOLD', 'T1w']}, 'dependencies': {'nilearn': '0.10.2'}, 'datareader': {'class': 'DefaultDataReader'}, 'type': 'BOLD', 'marker': {'agg_method': 'mean', 'agg_method_params': None, 'class': 'RSSETSMarker', 'masks': None, 'name': 'Schaefer100x17_RSSETS', 'parcellation': 'Schaefer100x17'}, '_element_keys': ['subject'], 'name': 'BOLD_Schaefer100x17_RSSETS'}, '24fef87855ff678fc17e53f2c2ab5e6e': {'datagrabber': {'class': 'SPMAuditoryTestingDataGrabber', 'types': ['BOLD', 'T1w']}, 'dependencies': {'nilearn': '0.10.2'}, 'datareader': {'class': 'DefaultDataReader'}, 'type': 'BOLD', 'marker': {'agg_method': 'mean', 'agg_method_params': None, 'class': 'RSSETSMarker', 'masks': None, 'name': 'Schaefer200x17_RSSETS', 'parcellation': 'Schaefer200x17'}, '_element_keys': ['subject'], 'name': 'BOLD_Schaefer200x17_RSSETS'}}

Now we take a look at the dataframe

root_sum_of_squares_ets
subject timepoint
sub001 0 1471.534513
1 78.624350
2 45.399273
3 69.362580
4 52.878724


Total running time of the script: (0 minutes 13.498 seconds)

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